CELA3A

Across TCGA cell cohorts, CELA3A mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CELA3A-associated genes across cancer lineages are MORC1, C20orf85, and OR1L4. Each is linked with CELA3A in more than 1 cancer types. Because this analysis shows association rather than direction, both CELA3A-to-partner and partner-to-CELA3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MORC1 grouped by CELA3A-low versus CELA3A-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELA3A→partner) and Y-score (partner→CELA3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MORC1 →	+0.100	+4.635	<.001	.003	3	1
SOFT_TISSUE	C20orf85 →	+0.086	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR1L4 →	+0.053	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR4D6 →	+0.035	+4.977	<.001	.002	3	1
SOFT_TISSUE	OR4X2 →	+0.024	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR51L1 →	+0.027	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

MORC1 by CELA3A expression — SOFT_TISSUE

Explore this box plot interactively →