CELA1

Across TCGA patient cohorts, CELA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,145 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CELA1-associated GO terms across cancer lineages are Regulation of leukocyte mediated immunity, Superoxide metabolic process, and Positive regulation of leukocyte cell-cell adhesion. Each is linked with CELA1 in more than 23 cancer types. Because this analysis shows association rather than direction, both CELA1-to-partner and partner-to-CELA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of leukocyte mediated immunity grouped by CELA1-low versus CELA1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CELA1→partner) and Y-score (partner→CELA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of leukocyte mediated immunity →	+0.056	+0.257	<.001	<.001	3	23
LAML	Superoxide metabolic process →	+0.073	+0.420	<.001	.007	2	24
STAD	Positive regulation of leukocyte cell-cell adhesion →	+0.071	+0.234	<.001	<.001	3	23
STAD	Myeloid leukocyte activation →	+0.054	+0.252	<.001	<.001	3	23
STAD	CD4-positive, alpha-beta T cell activation →	+0.061	+0.239	<.001	<.001	3	23
STAD	Regulation of leukocyte degranulation →	+0.059	+0.239	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,145 associations by consensus.

Regulation of leukocyte mediated immunity by CELA1 expression — STAD

Explore this box plot interactively →