CELA1

Across TCGA patient cohorts, CELA1 mutation is significantly associated with the RNA expression of many other genes, with 1,153 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CELA1-associated genes across cancer lineages are RNU6-1169P, TRDJ4, and RPL23AP27. Each is linked with CELA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CELA1-to-partner and partner-to-CELA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1169P grouped by CELA1-low versus CELA1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CELA1→partner) and Y-score (partner→CELA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1169P →	+0.438	+4.910	.001	.002	3	2
COAD	TRDJ4 →	+0.607	+5.122	<.001	.004	3	1
COAD	RPL23AP27 →	+0.198	+4.611	<.001	.004	3	1
COAD	HIGD1AP12 →	+0.280	+4.324	.001	.007	3	1
COAD	MIR8064 →	+0.660	+4.209	<.001	.009	3	1
COAD	MIR4477A →	+0.438	+6.142	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,153 associations by consensus.

RNU6-1169P by CELA1 expression — COAD

Explore this box plot interactively →