CELA1

Across TCGA cell cohorts, CELA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 543 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CELA1-associated GO terms across cancer lineages are Response to cortisol, Pre-B cell differentiation, and Endosome to lysosome transport via multivesicular body sorting pathway. Each is linked with CELA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CELA1-to-partner and partner-to-CELA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to cortisol grouped by CELA1-low versus CELA1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CELA1→partner) and Y-score (partner→CELA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Response to cortisol →	-0.278	-0.043	.001	.008	3	3
BLOOD_Leukemia	Pre-B cell differentiation →	-0.102	-0.149	.001	.003	3	3
LUNG_NSCLC_LUAD	Endosome to lysosome transport via multivesicular body sorting pathway →	+0.065	+0.058	<.001	.008	3	3
STOMACH	Glomerular epithelial cell development →	+0.257	+0.033	.001	.006	3	3
KIDNEY	Establishment of epithelial cell polarity →	+0.094	+0.018	.002	.009	3	3
BREAST	Positive regulation of antimicrobial humoral response →	+1.065	+0.043	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 543 associations by consensus.

Response to cortisol by CELA1 expression — BREAST

Explore this box plot interactively →