CECR2

Across TCGA pan-cancer cohorts, CECR2 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated CECR2 data layer compared with 20 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CECR2 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated CECR2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, HNSC, and ACC are the cancer types where CECR2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.948	0.607	.002	18	view →
HNSC	DFS	Median	All	0.294	0.632	.012	13	view →
ACC	OS	Median	All	0.268	0.802	.010	12	view →
LIHC	OS	Median	All	0.144	0.688	.013	9	view →
LUAD	DFS	Median	All	0.215	0.656	.015	8	view →
SCLC	OS	Median	All	0.444	0.726	.011	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SARC	DFS	Median	All	0.144	0.607	<.001	5	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CECR2–UCEC (DFS)

Open the UCEC breakdown →