Across TCGA pan-cancer cohorts, CEACAMP9 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CEACAMP9’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CEACAMP9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CEACAMP9 is over-expressed in tumor.
HNSC and LUSC are the cancer types where CEACAMP9 tumor–normal differential expression is most reproducible.