CEACAM8

Across TCGA patient cohorts, CEACAM8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,978 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CEACAM8-associated GO terms across cancer lineages are Actin filament bundle organization, Lipid homeostasis, and Regulation of cell projection assembly. Each is linked with CEACAM8 in more than 17 cancer types. Because this analysis shows association rather than direction, both CEACAM8-to-partner and partner-to-CEACAM8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament bundle organization grouped by CEACAM8-low versus CEACAM8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM8→partner) and Y-score (partner→CEACAM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Actin filament bundle organization →	+0.080	+0.266	<.001	<.001	3	18
STAD	Lipid homeostasis →	+0.036	+0.186	<.001	<.001	3	17
STAD	Regulation of cell projection assembly →	+0.078	+0.378	<.001	<.001	3	17
STAD	Iron ion transport →	+0.071	+0.323	<.001	<.001	3	16
STAD	Phospholipid biosynthetic process →	+0.053	+0.189	<.001	<.001	3	16
STAD	Glycerophospholipid biosynthetic process →	+0.089	+0.366	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,978 associations by consensus.

Actin filament bundle organization by CEACAM8 expression — STAD

Explore this box plot interactively →