CEACAM7

Across TCGA patient cohorts, CEACAM7 mutation is significantly associated with the RNA expression of many other genes, with 865 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEACAM7-associated genes across cancer lineages are SRRM1P2, RBM17P3, and RNU6-1114P. Each is linked with CEACAM7 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEACAM7-to-partner and partner-to-CEACAM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRRM1P2 grouped by CEACAM7-low versus CEACAM7-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM7→partner) and Y-score (partner→CEACAM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SRRM1P2 →	+0.073	+5.497	<.001	.004	3	3
HNSC	RBM17P3 →	+0.035	+4.327	<.001	.009	3	2
HNSC	RNU6-1114P →	+0.432	+4.182	<.001	.003	3	2
CESC	GSTA6P →	+0.080	+5.010	.006	.009	3	2
BLCA	MRPL49P1 →	+0.151	+5.899	<.001	.002	3	2
UCEC	ACTR5 →	+0.374	+3.700	.009	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 865 associations by consensus.

SRRM1P2 by CEACAM7 expression — BLCA

Explore this box plot interactively →