CEACAM7

Across TCGA cell cohorts, CEACAM7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,805 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CEACAM7-associated GO terms across cancer lineages are Bundle of His cell to Purkinje myocyte signaling, Bundle of His cell action potential, and Membrane depolarization during bundle of His cell action potential. Each is linked with CEACAM7 in more than 5 cancer types. Because this analysis shows association rather than direction, both CEACAM7-to-partner and partner-to-CEACAM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bundle of His cell to Purkinje myocyte signaling grouped by CEACAM7-low versus CEACAM7-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM7→partner) and Y-score (partner→CEACAM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Bundle of His cell to Purkinje myocyte signaling →	+0.813	+0.857	<.001	.003	3	5
BREAST	Bundle of His cell action potential →	+0.813	+0.857	<.001	.003	3	5
BREAST	Membrane depolarization during bundle of His cell action potential →	+0.727	+0.871	<.001	.003	3	5
LUNG_NSCLC_LUAD	Nucleoside metabolic process →	-0.077	-0.526	.002	.007	3	5
LARGE_INTESTINE	Response to Gram-positive bacterium →	+0.135	+1.231	.001	.006	3	5
BREAST	Secretion by tissue →	+0.288	+0.898	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,805 associations by consensus.

Bundle of His cell to Purkinje myocyte signaling by CEACAM7 expression — BREAST

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