CEACAM6

Across TCGA cell cohorts, CEACAM6 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEACAM6-associated genes across cancer lineages are PF4, AVP, and G6PC2. Each is linked with CEACAM6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM6-to-partner and partner-to-CEACAM6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PF4 grouped by CEACAM6-low versus CEACAM6-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM6→partner) and Y-score (partner→CEACAM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PF4 →	+0.031	+4.867	<.001	.009	3	1
LARGE_INTESTINE	AVP →	+0.056	+3.632	<.001	.003	3	1
LARGE_INTESTINE	G6PC2 →	+0.031	+3.658	.001	.005	3	1
LARGE_INTESTINE	MMP26 →	+0.039	+3.632	<.001	.003	3	1
LARGE_INTESTINE	ELOA3DP →	+0.030	+3.688	<.001	.002	3	1
LARGE_INTESTINE	FAM205A →	+0.020	+3.614	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

PF4 by CEACAM6 expression — BLOOD_Lymphoma

Explore this box plot interactively →