CEACAM5

Across TCGA patient cohorts, CEACAM5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,737 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CEACAM5-associated genes across cancer lineages are CEACAM6, FAM83E, and FOXA1. Each is linked with CEACAM5 in more than 6 cancer types. Because this analysis shows association rather than direction, both CEACAM5-to-partner and partner-to-CEACAM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEACAM5 versus CEACAM6 in LSCC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM5→partner) and Y-score (partner→CEACAM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CEACAM6 →	+2.803	+1.500	<.001	<.001	3	7
UCEC	FAM83E →	+1.439	+1.246	.001	.001	3	6
BRCA	FOXA1 →	+2.408	+1.131	<.001	.001	3	6
UCEC	SPACA4 →	+0.869	+1.278	.001	.001	3	6
BRCA	BCAS1 →	+1.275	+0.850	<.001	.001	3	6
LSCC	ST6GALNAC1 →	+1.813	+1.251	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,737 associations by consensus.

CEACAM5 vs CEACAM6 — LSCC

Explore this scatter interactively →