CEACAM5

Across TCGA cell cohorts, CEACAM5 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEACAM5-associated genes across cancer lineages are CLLU1-AS1, UNCX, and GSTA3. Each is linked with CEACAM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM5-to-partner and partner-to-CEACAM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLLU1-AS1 grouped by CEACAM5-low versus CEACAM5-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM5→partner) and Y-score (partner→CEACAM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CLLU1-AS1 →	+0.150	+3.977	<.001	.005	3	2
BLOOD_Myeloma	UNCX →	+0.006	+4.807	<.001	.006	3	1
PANCREAS	GSTA3 →	+0.025	+5.000	<.001	.006	3	1
PANCREAS	PRAMEF15 →	+0.023	+5.614	<.001	.002	3	1
PANCREAS	ZNF705G →	+0.049	+5.000	<.001	.006	3	1
PANCREAS	PRAMEF25 →	+0.016	+5.000	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

CLLU1-AS1 by CEACAM5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →