CEACAM4

Across TCGA patient cohorts, CEACAM4 protein abundance is significantly associated with the RNA expression of many other genes, with 430 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CEACAM4-associated genes across cancer lineages are RABAC1, PTPRZ1, and IRF4. Each is linked with CEACAM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM4-to-partner and partner-to-CEACAM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEACAM4 versus RABAC1 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM4→partner) and Y-score (partner→CEACAM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RABAC1 →	+0.536	+0.619	.007	.004	3	1
LSCC	PTPRZ1 →	-3.491	-0.796	.003	.006	3	1
LSCC	IRF4 →	+1.421	+0.584	.003	.008	3	1
LSCC	TRIM48 →	+0.177	+0.763	.003	.001	3	1
LSCC	C16orf86 →	+0.455	+0.673	.002	.001	3	1
LSCC	FRZB →	+1.173	+0.673	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 430 associations by consensus.

CEACAM4 vs RABAC1 — LSCC

Explore this scatter interactively →