CEACAM4

Across TCGA cell cohorts, CEACAM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,590 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CEACAM4-associated GO terms across cancer lineages are Dopamine biosynthetic process, Plus-end-directed vesicle transport along microtubule, and Negative regulation of fibroblast migration. Each is linked with CEACAM4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEACAM4-to-partner and partner-to-CEACAM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dopamine biosynthetic process grouped by CEACAM4-low versus CEACAM4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM4→partner) and Y-score (partner→CEACAM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Dopamine biosynthetic process →	-0.514	-0.682	.005	.009	3	3
BLOOD_Leukemia	Plus-end-directed vesicle transport along microtubule →	-0.364	-1.086	<.001	<.001	3	2
BLOOD_Leukemia	Negative regulation of fibroblast migration →	+0.073	+1.018	<.001	.002	3	2
BLOOD_Leukemia	Neutrophil extracellular trap formation →	+1.636	+1.277	<.001	<.001	3	2
BLOOD_Lymphoma	Cellular detoxification of metal ion →	-0.308	-0.012	.004	.006	3	2
BLOOD_Leukemia	Regulation of skeletal muscle contraction by calcium ion signaling →	+0.154	+0.932	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,590 associations by consensus.

Dopamine biosynthetic process by CEACAM4 expression — BLOOD_Leukemia

Explore this box plot interactively →