CEACAM3

Across TCGA patient cohorts, CEACAM3 mutation is significantly associated with the RNA expression of many other genes, with 606 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEACAM3-associated genes across cancer lineages are LAPTM4BP2, CCL27, and RPS10P21. Each is linked with CEACAM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM3-to-partner and partner-to-CEACAM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LAPTM4BP2 grouped by CEACAM3-low versus CEACAM3-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM3→partner) and Y-score (partner→CEACAM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LAPTM4BP2 →	+0.058	+3.283	.009	.003	3	2
UCEC	CCL27 →	+0.037	+4.354	<.001	<.001	3	2
UCEC	RPS10P21 →	+0.237	+2.202	.001	.002	3	2
UCEC	RNU7-29P →	+0.227	+3.606	<.001	.002	3	2
UCEC	RNU6-1213P →	+0.222	+3.761	<.001	.001	3	2
UCEC	ATP2A1-AS1 →	+1.187	+2.839	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 606 associations by consensus.

LAPTM4BP2 by CEACAM3 expression — LIHC

Explore this box plot interactively →