CEACAM3

Across TCGA cell cohorts, CEACAM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 396 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible CEACAM3-associated GO terms across cancer lineages are L-leucine import across plasma membrane, Cellular response to calcium ion starvation, and Homophilic cell-cell adhesion. Each is linked with CEACAM3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CEACAM3-to-partner and partner-to-CEACAM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-leucine import across plasma membrane grouped by CEACAM3-low versus CEACAM3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM3→partner) and Y-score (partner→CEACAM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	L-leucine import across plasma membrane →	-0.114	-0.128	.003	.002	3	3
LARGE_INTESTINE	Cellular response to calcium ion starvation →	+0.116	+0.067	<.001	.002	2	4
PANCREAS	Homophilic cell-cell adhesion →	+0.125	+0.152	<.001	<.001	3	3
PANCREAS	AV node cell action potential →	+0.883	+0.136	.001	.001	3	3
PANCREAS	AV node cell to bundle of His cell signaling →	+0.883	+0.136	.001	.001	3	3
PANCREAS	Membrane depolarization during AV node cell action potential →	+0.978	+0.170	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 396 associations by consensus.

L-leucine import across plasma membrane by CEACAM3 expression — BREAST

Explore this box plot interactively →