CEACAM21

Across TCGA patient cohorts, CEACAM21 mutation is significantly associated with the RNA expression of many other genes, with 1,364 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CEACAM21-associated genes across cancer lineages are CCDC34, MIR1273C, and RN7SKP1. Each is linked with CEACAM21 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEACAM21-to-partner and partner-to-CEACAM21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC34 grouped by CEACAM21-low versus CEACAM21-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM21→partner) and Y-score (partner→CEACAM21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CCDC34 →	+0.602	+3.472	.001	.002	3	3
UCEC	MIR1273C →	+0.438	+1.694	.002	.007	3	2
LUSC	RN7SKP1 →	+0.268	+3.816	.003	.002	3	2
LUAD	RNU6-61P →	+0.347	+6.087	<.001	.002	3	2
LUSC	LINC00555 →	+0.124	+3.220	.001	.002	3	2
LUSC	MIR5584 →	+0.254	+4.148	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,364 associations by consensus.

CCDC34 by CEACAM21 expression — SKCM

Explore this box plot interactively →