CEACAM21

Across TCGA cell cohorts, CEACAM21 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,974 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CEACAM21-associated GO terms across cancer lineages are Positive regulation of epidermal cell differentiation, Establishment of protein localization to chromatin, and Regulation of systemic arterial blood pressure mediated by a chemical signal. Each is linked with CEACAM21 in more than 5 cancer types. Because this analysis shows association rather than direction, both CEACAM21-to-partner and partner-to-CEACAM21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of epidermal cell differentiation grouped by CEACAM21-low versus CEACAM21-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM21→partner) and Y-score (partner→CEACAM21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of epidermal cell differentiation →	+0.238	+1.689	<.001	.001	3	6
BONE	Establishment of protein localization to chromatin →	+0.095	+1.599	.003	.002	3	6
BONE	Regulation of systemic arterial blood pressure mediated by a chemical signal →	-0.219	-2.056	<.001	.001	3	5
BONE	Cell junction assembly →	-0.053	-2.492	.002	.004	3	5
BONE	Chaperone-mediated autophagy →	-0.160	-1.493	<.001	.003	3	5
SOFT_TISSUE	Regulation of interleukin-6-mediated signaling pathway →	-0.116	-1.475	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,974 associations by consensus.

Positive regulation of epidermal cell differentiation by CEACAM21 expression — BONE

Explore this box plot interactively →