CEACAM21

Across TCGA cell cohorts, CEACAM21 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEACAM21-associated genes across cancer lineages are FAM187B, C9orf92, and OR10G2. Each is linked with CEACAM21 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM21-to-partner and partner-to-CEACAM21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM187B grouped by CEACAM21-low versus CEACAM21-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM21→partner) and Y-score (partner→CEACAM21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FAM187B →	+0.044	+3.684	<.001	.006	3	1
SKIN	C9orf92 →	+0.094	+4.347	<.001	.001	3	1
SKIN	OR10G2 →	+0.014	+4.437	<.001	.004	3	1
CNS	GAGE12D →	+1.186	+6.357	<.001	<.001	3	1
CNS	GAGE12C →	+1.186	+6.357	<.001	<.001	3	1
LARGE_INTESTINE	CRP →	+0.089	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

FAM187B by CEACAM21 expression — SKIN

Explore this box plot interactively →