Across TCGA patient cohorts, CEACAM19 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEACAM19-associated genes across cancer lineages are INPP4B, IGFBP2, and JNK2. Each is linked with CEACAM19 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM19-to-partner and partner-to-CEACAM19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM19→partner) and Y-score (partner→CEACAM19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	INPP4B →	-0.188	-3.442	.049	.005	3	1
UCEC	IGFBP2 →	-0.772	-2.000	.008	.032	3	1
UCEC	JNK2 →	+0.248	+2.700	.005	.006	3	1
UCEC	MSH2 →	-0.276	-2.973	.007	.035	3	1
UCEC	mTOR_pS2448 →	-0.153	-3.308	.023	.009	3	1
UCEC	PDCD4 →	-0.425	-2.312	.045	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

CEACAM19 survival (RNA) · tumor vs normal (RNA) · all CEACAM19 data types