Across TCGA patient cohorts, CEACAM16 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEACAM16-associated genes across cancer lineages are EGFR_pY1068, JNK2, and mTOR_pS2448. Each is linked with CEACAM16 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM16-to-partner and partner-to-CEACAM16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM16→partner) and Y-score (partner→CEACAM16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.248	-2.321	.049	.035	3	1
UCEC	JNK2 →	+0.343	+3.009	<.001	.019	3	1
UCEC	mTOR_pS2448 →	-0.212	-2.980	.004	.036	3	1
UCEC	Notch1 →	+0.229	+2.321	.001	.035	3	1
UCEC	PDCD4 →	-0.597	-2.321	.011	.035	3	1
UCEC	STAT3_pY705 →	-0.504	-2.321	<.001	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

CEACAM16 survival (RNA) · tumor vs normal (RNA) · all CEACAM16 data types