Across TCGA cell cohorts, CEACAM16 mutation is significantly associated with the drug of many other genes, with 34 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEACAM16-associated genes across cancer lineages are RVX-208, Dinaciclib, and PAK_5339. Each is linked with CEACAM16 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEACAM16-to-partner and partner-to-CEACAM16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEACAM16→partner) and Y-score (partner→CEACAM16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RVX-208 →	+0.476	+2.646	.001	.047	3	1
LARGE_INTESTINE	Dinaciclib →	+0.525	+2.646	.042	.047	2	1
LARGE_INTESTINE	PAK_5339 →	+0.371	+2.678	.012	.037	2	1
LARGE_INTESTINE	Mitoxantrone →	+0.764	+2.649	.009	.046	2	1
LARGE_INTESTINE	729189 →	+0.300	+2.649	.018	.046	2	1
LARGE_INTESTINE	Alectinib →	+0.422	+2.786	.013	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

CEACAM16 survival (RNA) · tumor vs normal (RNA) · all CEACAM16 data types