CDYL2

Across TCGA cell cohorts, CDYL2 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDYL2-associated genes across cancer lineages are TEX26, GAGE12D, and GAGE12C. Each is linked with CDYL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDYL2-to-partner and partner-to-CDYL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX26 grouped by CDYL2-low versus CDYL2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDYL2→partner) and Y-score (partner→CDYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TEX26 →	+0.094	+4.044	<.001	.009	3	1
LUNG_SCLC	GAGE12D →	+0.442	+4.643	<.001	.004	3	1
LUNG_SCLC	GAGE12C →	+0.442	+4.643	<.001	.004	3	1
BLOOD_Leukemia	TP53AIP1 →	+0.085	+3.504	<.001	.004	3	1
BLOOD_Leukemia	LMX1A →	+0.082	+2.824	.002	.007	3	1
BLOOD_Leukemia	DEFB108B →	+0.083	+3.684	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

TEX26 by CDYL2 expression — LUNG_SCLC

Explore this box plot interactively →