CDYL

Across TCGA patient cohorts, CDYL protein abundance is significantly associated with the RNA expression of many other genes, with 16,331 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDYL-associated genes across cancer lineages are NUP153, GMNN, and PRPF4B. Each is linked with CDYL in more than 8 cancer types. Because this analysis shows association rather than direction, both CDYL-to-partner and partner-to-CDYL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDYL versus NUP153 in HNSC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDYL→partner) and Y-score (partner→CDYL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUP153 →	+0.821	+0.378	<.001	<.001	3	9
COAD	GMNN →	+0.788	+0.404	.008	.005	3	8
HNSC	PRPF4B →	+0.872	+0.333	<.001	<.001	3	8
HNSC	WRNIP1 →	+0.684	+0.239	<.001	<.001	3	8
LSCC	RIOK1 →	+0.833	+0.425	<.001	<.001	3	8
LSCC	DEK →	+0.751	+0.348	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,331 associations by consensus.

CDYL vs NUP153 — HNSC

Explore this scatter interactively →