CDYL

Across TCGA patient cohorts, CDYL mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDYL-associated genes across cancer lineages are eIF4E, mTOR_pS2448, and FASN. Each is linked with CDYL in more than 2 cancer types. Because this analysis shows association rather than direction, both CDYL-to-partner and partner-to-CDYL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by CDYL-low versus CDYL-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDYL→partner) and Y-score (partner→CDYL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eIF4E →	+0.190	+2.484	.014	.010	3	3
UCEC	mTOR_pS2448 →	-0.103	-1.664	.024	.019	3	3
STAD	FASN →	+0.499	+2.823	.028	.034	2	3
UCEC	FoxM1 →	+0.160	+1.947	.044	<.001	3	2
COAD	GAPDH →	+0.495	+2.467	.024	.011	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.395	-1.460	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

eIF4E by CDYL expression — COAD

Explore this box plot interactively →