CDYL-AS1

Across TCGA pan-cancer cohorts, CDYL-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated CDYL-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CDYL-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CDYL-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.

UCEC, ACC, and UVM are the cancer types where CDYL-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.580	0.783	<.001	90	view →
ACC	DFS	Tertile	All	0.158	0.538	<.001	82	view →
UVM	DFS	Tertile	III,IV	0.856	0.243	.004	76	view →
STAD	OS	Tertile	IV	0.135	0.550	<.001	45	view →
UCS	DFS	Quartile	II,III,IV	0.720	0.343	.012	40	view →
MESO	OS	Tertile	IV	0.217	0.655	.016	36	view →
KIRP	DFS	Tertile	IV	0.088	0.502	<.001	36	view →
TGCT	DFS	Tertile	II,III,IV	0.678	0.996	.015	30	view →
OV	OS	Median	IV	0.876	0.637	.002	20	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
LGG	OS	Tertile	All	0.309	0.484	.009	18	view →
KICH	OS	Tertile	II,III,IV	0.683	0.918	.026	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

CDYL-AS1–UCEC (DFS)

Open the UCEC breakdown →