CDX2

Across TCGA patient cohorts, CDX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,980 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible CDX2-associated GO terms across cancer lineages are Mitochondrial gene expression, Fatty-acyl-CoA metabolic process, and Mitochondrial translation. Each is linked with CDX2 in more than 11 cancer types. Because this analysis shows association rather than direction, both CDX2-to-partner and partner-to-CDX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by CDX2-low versus CDX2-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDX2→partner) and Y-score (partner→CDX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Mitochondrial gene expression →	+0.034	+0.035	<.001	<.001	3	12
SCLC	Fatty-acyl-CoA metabolic process →	+0.059	+0.752	.005	.003	3	12
KIRC	Mitochondrial translation →	+0.036	+0.028	<.001	<.001	3	11
LUSC	RNA capping →	+0.028	+0.436	<.001	<.001	3	11
TGCT	Obsolete histone deacetylation →	+0.040	+1.707	<.001	<.001	3	10
TGCT	Regulation of mitochondrial membrane permeability →	+0.035	+0.987	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,980 associations by consensus.

Mitochondrial gene expression by CDX2 expression — KIRC

Explore this box plot interactively →