CDX2

Across TCGA patient cohorts, CDX2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,119 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CDX2-associated genes across cancer lineages are SEC14L2, CYTH4, and EIF3L. Each is linked with CDX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDX2-to-partner and partner-to-CDX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDX2 versus SEC14L2 in COAD, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDX2→partner) and Y-score (partner→CDX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SEC14L2 →	-0.439	-0.511	.003	<.001	3	1
COAD	CYTH4 →	-0.634	-0.459	.001	<.001	3	1
COAD	EIF3L →	-0.420	-0.432	.001	<.001	3	1
COAD	KDELR3 →	-0.622	-0.358	<.001	<.001	3	1
COAD	HSCB →	-0.503	-0.476	<.001	<.001	3	1
COAD	MIOX →	-0.649	-0.391	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,119 associations by consensus.

CDX2 vs SEC14L2 — COAD

Explore this scatter interactively →