CDX1

Across TCGA patient cohorts, CDX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,919 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDX1-associated proteins across cancer lineages are CPXM1, SIPA1, and ZEB2. Each is linked with CDX1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CDX1-to-partner and partner-to-CDX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDX1 versus CPXM1 in BRCA, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDX1→partner) and Y-score (partner→CDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CPXM1 →	+0.643	+0.258	<.001	<.001	3	5
GBM	SIPA1 →	+0.248	+0.148	<.001	<.001	3	4
OV	ZEB2 →	+0.384	+0.319	<.001	.001	3	4
OV	CLIP2 →	+0.638	+0.358	<.001	.002	3	4
GBM	COL3A1 →	+0.924	+0.218	<.001	<.001	3	4
LSCC	COL5A2 →	+0.693	+0.438	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,919 associations by consensus.

CDX1 vs CPXM1 — BRCA

Explore this scatter interactively →