CDX1

Across TCGA patient cohorts, CDX1 protein abundance is significantly associated with the RNA expression of many other genes, with 702 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDX1-associated genes across cancer lineages are EEF1D, PDE4C, and PON3. Each is linked with CDX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDX1-to-partner and partner-to-CDX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDX1 versus EEF1D in COAD, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDX1→partner) and Y-score (partner→CDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EEF1D →	-0.281	-0.302	.002	.002	3	1
COAD	PDE4C →	+0.061	+0.306	.002	.002	3	1
COAD	PON3 →	-1.066	-0.423	.002	.001	3	1
COAD	CHRNE →	-0.256	-0.431	.002	<.001	3	1
COAD	SLC16A6 →	-0.324	-0.278	.008	.005	3	1
COAD	VWA5A →	+0.572	+0.333	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 702 associations by consensus.

CDX1 vs EEF1D — COAD

Explore this scatter interactively →