CDT1

Across TCGA cell cohorts, CDT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,510 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CDT1-associated GO terms across cancer lineages are Cell cycle DNA replication initiation, Nuclear cell cycle DNA replication initiation, and Mitotic DNA replication initiation. Each is linked with CDT1 in more than 19 cancer types. Because this analysis shows association rather than direction, both CDT1-to-partner and partner-to-CDT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell cycle DNA replication initiation grouped by CDT1-low versus CDT1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDT1→partner) and Y-score (partner→CDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cell cycle DNA replication initiation →	+0.199	+1.443	<.001	<.001	3	20
URINARY_TRACT	Nuclear cell cycle DNA replication initiation →	+0.199	+1.443	<.001	<.001	3	20
URINARY_TRACT	Mitotic DNA replication initiation →	+0.199	+1.443	<.001	<.001	3	20
BONE	Cell cycle DNA replication →	+0.208	+1.733	<.001	.002	3	19
URINARY_TRACT	Mitotic DNA replication →	+0.221	+1.515	<.001	<.001	3	19
BONE	Nuclear DNA replication →	+0.179	+1.428	<.001	.003	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,510 associations by consensus.

Cell cycle DNA replication initiation by CDT1 expression — URINARY_TRACT

Explore this box plot interactively →