CDS1

Across TCGA cell cohorts, CDS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,361 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDS1-associated GO terms across cancer lineages are Negative regulation of Arp2/3 complex-mediated actin nucleation, Establishment of epithelial cell apical/basal polarity, and Positive regulation of endothelial cell development. Each is linked with CDS1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CDS1-to-partner and partner-to-CDS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of Arp2/3 complex-mediated actin nucleation grouped by CDS1-low versus CDS1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDS1→partner) and Y-score (partner→CDS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.190	+1.997	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.236	-1.806	<.001	<.001	3	11
URINARY_TRACT	Positive regulation of endothelial cell development →	+0.256	+2.413	<.001	<.001	3	11
OVARY	Protein localization to bicellular tight junction →	+0.137	+1.685	<.001	<.001	3	11
URINARY_TRACT	Positive regulation of establishment of endothelial barrier →	+0.256	+2.413	<.001	<.001	3	11
OVARY	Bundle of His cell to Purkinje myocyte communication →	+0.367	+2.088	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,361 associations by consensus.

Negative regulation of Arp2/3 complex-mediated actin nucleation by CDS1 expression — STOMACH

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