CDRT4

Across TCGA cell cohorts, CDRT4 mutation is significantly associated with the mutation status of many other genes, with 57 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDRT4-associated genes across cancer lineages are ARHGDIG, OAZ1, and CCN2. Each is linked with CDRT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDRT4-to-partner and partner-to-CDRT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARHGDIG grouped by CDRT4-low versus CDRT4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDRT4→partner) and Y-score (partner→CDRT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARHGDIG →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	OAZ1 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	CCN2 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	FAM117A →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	ZNF32 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	RNF148 →	+4.523	+5.087	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

ARHGDIG by CDRT4 expression — LARGE_INTESTINE

Explore this box plot interactively →