CDRT1

Across TCGA cell cohorts, CDRT1 mutation is significantly associated with the drug of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDRT1-associated genes across cancer lineages are 123829, KRAS (G12C) Inhibitor-12, and PRT062607. Each is linked with CDRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDRT1-to-partner and partner-to-CDRT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 123829 grouped by CDRT1-low versus CDRT1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDRT1→partner) and Y-score (partner→CDRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	123829 →	+0.622	+2.649	.032	.046	3	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.695	+2.646	.004	.047	3	1
LARGE_INTESTINE	PRT062607 →	+0.638	+2.769	.010	.040	2	1
LARGE_INTESTINE	Dinaciclib →	+0.543	+2.646	.035	.047	1	1
LARGE_INTESTINE	Teniposide →	+0.736	+2.649	.005	.046	1	1
LARGE_INTESTINE	Dactinomycin →	+0.616	+2.649	.007	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

123829 by CDRT1 expression — LARGE_INTESTINE

Explore this box plot interactively →