CDR2L

Across TCGA cell cohorts, CDR2L mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDR2L-associated genes across cancer lineages are BMF, SELENOK, and CCT4. Each is linked with CDR2L in more than 1 cancer types. Because this analysis shows association rather than direction, both CDR2L-to-partner and partner-to-CDR2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMF grouped by CDR2L-low versus CDR2L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDR2L→partner) and Y-score (partner→CDR2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BMF →	-1.176	-3.278	<.001	.006	3	1
LARGE_INTESTINE	SELENOK →	+0.543	+3.364	.004	.002	3	1
LARGE_INTESTINE	CCT4 →	+0.530	+3.364	.003	.002	3	1
LARGE_INTESTINE	CCDC92 →	-0.889	-3.278	.001	.006	3	1
LARGE_INTESTINE	MTX2 →	+0.324	+3.364	.006	.002	3	1
LARGE_INTESTINE	PSMG2 →	+0.592	+3.451	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

BMF by CDR2L expression — LARGE_INTESTINE

Explore this box plot interactively →