CDR2

Across TCGA cell cohorts, CDR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,292 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDR2-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Negative regulation of plasma membrane bounded cell projection assembly, and Regulation of Golgi inheritance. Each is linked with CDR2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDR2-to-partner and partner-to-CDR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle cargo loading grouped by CDR2-low versus CDR2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDR2→partner) and Y-score (partner→CDR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	COPII-coated vesicle cargo loading →	+0.134	+0.749	<.001	<.001	3	10
BONE	Negative regulation of plasma membrane bounded cell projection assembly →	+0.048	+0.618	<.001	<.001	3	10
URINARY_TRACT	Regulation of Golgi inheritance →	+0.133	+0.825	.001	.001	3	10
BONE	Vesicle cargo loading →	+0.134	+0.617	<.001	.003	3	9
BONE	Protein targeting to membrane →	+0.062	+0.928	.005	<.001	3	9
LUNG_NSCLC_LUAD	Peptidyl-arginine modification →	-0.120	-0.993	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,292 associations by consensus.

COPII-coated vesicle cargo loading by CDR2 expression — BONE

Explore this box plot interactively →