Across TCGA patient cohorts, CDR1 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDR1-associated genes across cancer lineages are ACC1, TFRC, and ATM. Each is linked with CDR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDR1-to-partner and partner-to-CDR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDR1→partner) and Y-score (partner→CDR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.312	+1.415	.022	.046	3	3
SKCM	TFRC →	+0.526	+1.874	.013	.049	3	2
UCEC	ATM →	-0.550	-2.169	.001	.003	3	2
UCEC	Caspase-7-cleavedD198 →	+0.668	+2.720	.002	.003	3	2
UCEC	eEF2 →	+0.272	+1.874	.042	.049	3	1
UCEC	ER-alpha_pS118 →	-0.276	-1.765	.040	.014	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

CDR1 survival (RNA) · tumor vs normal (RNA) · all CDR1 data types