CDON

Across TCGA cell cohorts, CDON RNA expression is significantly associated with the go_rna of many other GO terms, with 5,009 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CDON-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of smoothened signaling pathway. Each is linked with CDON in more than 13 cancer types. Because this analysis shows association rather than direction, both CDON-to-partner and partner-to-CDON results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CDON-low versus CDON-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDON→partner) and Y-score (partner→CDON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.105	+1.262	.008	.002	3	14
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+1.032	<.001	<.001	3	14
STOMACH	Regulation of smoothened signaling pathway →	+0.062	+1.135	<.001	.003	2	14
STOMACH	Positive regulation of double-strand break repair →	+0.095	+1.776	.001	<.001	3	13
STOMACH	Regulation of nucleotide-excision repair →	+0.143	+1.654	.001	<.001	3	13
BLOOD_Leukemia	Regulation of transcription initiation by RNA polymerase II →	+0.054	+0.901	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,009 associations by consensus.

Negative regulation of myoblast fusion by CDON expression — STOMACH

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