Across TCGA patient cohorts, CDNF protein abundance is significantly associated with the RNA expression of many other genes, with 2,781 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CDNF-associated genes across cancer lineages are GPSM2, NABP2, and RBFOX1. Each is linked with CDNF in more than 1 cancer types. Because this analysis shows association rather than direction, both CDNF-to-partner and partner-to-CDNF results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDNF→partner) and Y-score (partner→CDNF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPSM2 →	-0.881	-0.802	.002	.009	3	2
OV	NABP2 →	-0.446	-0.661	.001	.004	3	2
HNSC	RBFOX1 →	+0.979	+1.005	<.001	<.001	3	2
BRCA	UBE2S →	-0.822	-0.323	.002	.008	3	2
HNSC	AMPD1 →	+1.096	+0.581	<.001	<.001	3	2
HNSC	CASQ2 →	+1.967	+0.655	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,781 associations by consensus.

Exploration

CDNF survival (RNA) · tumor vs normal (RNA) · all CDNF data types