CDKN2C

Across TCGA patient cohorts, CDKN2C mutation is significantly associated with the RNA expression of many other genes, with 652 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDKN2C-associated genes across cancer lineages are SNORD3G, RNA5SP175, and RNU6-1026P. Each is linked with CDKN2C in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKN2C-to-partner and partner-to-CDKN2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD3G grouped by CDKN2C-low versus CDKN2C-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2C→partner) and Y-score (partner→CDKN2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	SNORD3G →	+0.178	+5.760	<.001	.003	3	2
UCEC	RNA5SP175 →	+1.180	+2.189	<.001	.006	3	2
UCEC	RNU6-1026P →	+0.230	+3.200	.006	.006	3	2
UCEC	RNA5SP436 →	+0.533	+3.767	<.001	<.001	3	2
UCEC	NCAPD3 →	+0.707	+3.595	.003	.001	3	1
UCEC	GUF1 →	+0.529	+3.595	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 652 associations by consensus.

SNORD3G by CDKN2C expression — LGG

Explore this box plot interactively →