CDKN2B

Across TCGA patient cohorts, CDKN2B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,137 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CDKN2B-associated proteins across cancer lineages are CDKN2A, PLXDC2, and PRKG1. Each is linked with CDKN2B in more than 6 cancer types. Because this analysis shows association rather than direction, both CDKN2B-to-partner and partner-to-CDKN2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKN2B versus CDKN2A in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2B→partner) and Y-score (partner→CDKN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDKN2A →	+1.122	+1.474	<.001	<.001	3	7
BRCA	PLXDC2 →	+0.713	+1.168	<.001	<.001	3	6
CCRCC	PRKG1 →	+0.613	+0.790	<.001	<.001	3	6
GBM	MTAP →	+0.777	+2.523	<.001	<.001	3	6
COAD	RSU1 →	+0.420	+0.852	.001	.001	3	5
COAD	ILK →	+0.473	+0.886	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,137 associations by consensus.

CDKN2B vs CDKN2A — OV

Explore this scatter interactively →