CDKN2B

Across TCGA patient cohorts, CDKN2B protein abundance is significantly associated with the RNA expression of many other genes, with 2,933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDKN2B-associated genes across cancer lineages are CCDC150, BNIP3P24, and STMN2. Each is linked with CDKN2B in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKN2B-to-partner and partner-to-CDKN2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKN2B versus CCDC150 in COAD, with a Pearson correlation of -0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2B→partner) and Y-score (partner→CDKN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CCDC150 →	-0.465	-0.740	<.001	.006	3	2
LUAD	BNIP3P24 →	-0.828	-0.445	.007	.009	3	2
BRCA	STMN2 →	+1.691	+1.096	.001	.003	3	2
OV	BEST1 →	+0.496	+0.895	.004	.002	3	2
LSCC	C6orf52 →	-0.649	-0.505	<.001	<.001	3	2
HNSC	RNFT1P3 →	-0.714	-0.401	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,933 associations by consensus.

CDKN2B vs CCDC150 — COAD

Explore this scatter interactively →