Across TCGA pan-cancer cohorts, CDKN2AIPNLP2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of CDKN2AIPNLP2’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where CDKN2AIPNLP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CDKN2AIPNLP2 is over-expressed in tumor.
STAD are the cancer types where CDKN2AIPNLP2 tumor–normal differential expression is most reproducible.