CDKN2AIPNLP1

Across TCGA pan-cancer cohorts, CDKN2AIPNLP1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CDKN2AIPNLP1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CDKN2AIPNLP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CDKN2AIPNLP1 expression acts as an unfavorable survival marker, although some lineages such as GBM and SKCM show a favorable association.

UVM, MESO, and HNSC are the cancer types where CDKN2AIPNLP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.281	0.751	<.001	84	view →
MESO	OS	Tertile	IV	0.036	0.602	<.001	45	view →
HNSC	DFS	Tertile	II,III,IV	0.228	0.355	.019	39	view →
ACC	DFS	Tertile	IV	0.012	0.310	.002	34	view →
GBM	DFS	Tertile	All	0.302	0.134	<.001	21	view →
SKCM	DFS	Tertile	All	0.789	0.578	.001	21	view →
LIHC	OS	Tertile	All	0.634	0.809	.006	15	view →
OV	DFS	Tertile	IV	0.473	0.224	.011	12	view →
BRCA	DFS	Tertile	II,III,IV	0.970	0.933	.015	12	view →
ESCA	DFS	Quartile	II,III,IV	0.140	1.000	.006	12	view →
LAML	DFS	Tertile	All	0.420	0.621	.033	12	view →
STAD	DFS	Tertile	IV	0.731	0.213	.039	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CDKN2AIPNLP1–UVM (OS)

Open the UVM breakdown →