CDKN2AIP

Across TCGA cell cohorts, CDKN2AIP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,044 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CDKN2AIP-associated GO terms across cancer lineages are Negative regulation of mitotic cell cycle, Regulation of cellular response to transforming growth factor beta stimulus, and Centrosome duplication. Each is linked with CDKN2AIP in more than 10 cancer types. Because this analysis shows association rather than direction, both CDKN2AIP-to-partner and partner-to-CDKN2AIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mitotic cell cycle grouped by CDKN2AIP-low versus CDKN2AIP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2AIP→partner) and Y-score (partner→CDKN2AIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic cell cycle →	+0.069	+0.792	<.001	<.001	3	11
SKIN	Regulation of cellular response to transforming growth factor beta stimulus →	+0.042	+0.474	<.001	.007	3	11
UPPER_AERODIGESTIVE_TRACT	Centrosome duplication →	+0.084	+0.694	.001	.008	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic cell cycle phase transition →	+0.076	+0.914	<.001	<.001	3	11
BONE	Epigenetic regulation of gene expression →	+0.060	+0.597	.005	.001	3	11
SOFT_TISSUE	Protein modification by small protein removal →	+0.050	+0.477	.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,044 associations by consensus.

Negative regulation of mitotic cell cycle by CDKN2AIP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →