CDKL3

Across TCGA patient cohorts, CDKL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,438 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDKL3-associated proteins across cancer lineages are C5orf24, PHAX, and SMAD5. Each is linked with CDKL3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDKL3-to-partner and partner-to-CDKL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKL3 versus C5orf24 in OV, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKL3→partner) and Y-score (partner→CDKL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C5orf24 →	+0.348	+0.270	<.001	.001	3	6
GBM	PHAX →	+0.347	+0.463	<.001	<.001	3	6
BRCA	SMAD5 →	+0.290	+0.303	<.001	<.001	3	5
GBM	SUGP2 →	+0.453	+0.442	<.001	<.001	3	5
BRCA	ING4 →	+0.543	+0.422	<.001	<.001	3	5
BRCA	VEZF1 →	+0.461	+0.422	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,438 associations by consensus.

CDKL3 vs C5orf24 — OV

Explore this scatter interactively →