CDKL3

Across TCGA cell cohorts, CDKL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,310 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible CDKL3-associated GO terms across cancer lineages are COPII-coated vesicle budding, Vesicle targeting, rough ER to cis-Golgi, and COPII vesicle coating. Each is linked with CDKL3 in more than 13 cancer types. Because this analysis shows association rather than direction, both CDKL3-to-partner and partner-to-CDKL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle budding grouped by CDKL3-low versus CDKL3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKL3→partner) and Y-score (partner→CDKL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	COPII-coated vesicle budding →	+0.096	+0.700	<.001	<.001	3	14
BONE	Vesicle targeting, rough ER to cis-Golgi →	+0.108	+0.833	.001	.002	3	12
BONE	COPII vesicle coating →	+0.115	+1.100	<.001	<.001	3	12
OVARY	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.071	+0.830	<.001	<.001	3	12
LUNG_SCLC	Vesicle coating →	+0.089	+0.580	.007	.003	2	13
KIDNEY	Glycophagy →	+0.110	+0.991	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,310 associations by consensus.

COPII-coated vesicle budding by CDKL3 expression — STOMACH

Explore this box plot interactively →