CDKL1

Across TCGA patient cohorts, CDKL1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,229 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CDKL1-associated genes across cancer lineages are CSF2RB, TLR8, and TNFSF13B. Each is linked with CDKL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKL1-to-partner and partner-to-CDKL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKL1 versus CSF2RB in OV, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKL1→partner) and Y-score (partner→CDKL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CSF2RB →	+2.047	+1.392	.002	.004	3	1
OV	TLR8 →	+2.165	+1.277	.001	.008	3	1
OV	TNFSF13B →	+2.027	+1.409	.004	.009	3	1
OV	NUTF2 →	+0.513	+0.969	.006	.006	3	1
OV	PRPF31 →	-0.659	-1.242	.007	.006	3	1
OV	FMO1 →	+1.433	+1.024	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,229 associations by consensus.

CDKL1 vs CSF2RB — OV

Explore this scatter interactively →