CDKAL1

Across TCGA patient cohorts, CDKAL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,724 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDKAL1-associated proteins across cancer lineages are NUP153, DHX9, and GNL1. Each is linked with CDKAL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDKAL1-to-partner and partner-to-CDKAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKAL1 versus NUP153 in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKAL1→partner) and Y-score (partner→CDKAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NUP153 →	+0.379	+0.879	<.001	<.001	3	9
LSCC	DHX9 →	+0.247	+0.736	<.001	<.001	3	7
LSCC	GNL1 →	+0.420	+0.968	<.001	<.001	3	7
GBM	HCFC1 →	+0.206	+0.293	<.001	<.001	3	7
LSCC	HDAC2 →	+0.415	+1.053	<.001	<.001	3	7
LSCC	PRRC2A →	+0.349	+1.042	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,724 associations by consensus.

CDKAL1 vs NUP153 — BRCA

Explore this scatter interactively →