CDKAL1

Across TCGA patient cohorts, CDKAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,839 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDKAL1-associated genes across cancer lineages are MYBL2, TTK, and FOXM1. Each is linked with CDKAL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDKAL1-to-partner and partner-to-CDKAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDKAL1 versus MYBL2 in LUAD, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKAL1→partner) and Y-score (partner→CDKAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MYBL2 →	+1.354	+0.248	<.001	<.001	3	9
OV	TTK →	+1.201	+0.344	<.001	.003	3	9
BRCA	FOXM1 →	+1.033	+0.223	<.001	<.001	3	8
LSCC	E2F3 →	+0.683	+0.336	<.001	<.001	3	8
BRCA	ABCA8 →	-1.272	-0.459	<.001	<.001	3	8
LSCC	DTL →	+0.941	+0.418	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,839 associations by consensus.

CDKAL1 vs MYBL2 — LUAD

Explore this scatter interactively →